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The concentration-dependent [Ca2+]i elevation and the NO production induced by bradykinin (A), thrombin (B) and ionomycin (C). The peak [Ca2+]i elevation, the integrated [Ca2+]i elevation and the NO production in the absence (control) and presence of 3 mM NΩ-monomethyl-L-arginine (L-NMMA) and 1 μM fendiline. L-NMMA and fendiline were applied 10 min before the stimulation. The data are the mean±s.e.mean (n=4–11). *Significantly different (P<0.05); n.s., not significant (P>0.05).
