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. 2000 Jul;130(6):1201–1210. doi: 10.1038/sj.bjp.0703413

Figure 5.

Figure 5

Time-course for the reduction of working memory after Δ9-tetrahydrocannabinol administration (For the number of correct entries: ANOVA main effect Δ9-THC2.5 mg kg−1 F1.8=44.41, P<0.001; ANOVA main effect of repeated measures Δ9-THC2.5 mg kg−1 F4.20=0.95, P=0.45; ANOVA main effect Δ9-THC5 mg kg−1 F1.8=62.45, P<0.0001; ANOVA main effect of repeated measures Δ9-THC5 mg kg−1 F4.20=0.93, P=0.46; ANOVA main effect Δ9-THC7.5 mg kg−1 F1.8=36.62, P<0.001; ANOVA main effect of repeated measures Δ9-THC7.5 mg kg−1 F4.20=1.06, P=0.40; For the number of incorrect entries: ANOVA main effect Δ9-THC2.5 mg kg−1 F1.8=44.11, P<0.0001; ANOVA main effect of repeated measures Δ9-THC2.5 mg kg−1 F4.20=0.95, P<0.45; ANOVA main effect Δ9-THC5 mg kg−1 F1.8=58.87, P<0.0001; ANOVA main effect of repeated measures Δ9-THC5 mg kg−1 F4.20=0.86, P=0.50; ANOVA main effect Δ9-THC7.5 mg kg−1 F1.8=36.45, P<0.001; ANOVA main effect of repeated measures Δ9-THC7.5 mg kg−1 F4.20=1.03, P=0.41). Data are expressed as number of correct and incorrect entries (mean±s.e.mean; n=5) in T-maze on 10 trials. A Δ9-tetrahydrocannabinol dose of 1 mg kg−1 had no effect on delayed alternation tasks in the T-maze. Intertrial delay was fixed at 8 s. s.e. values were not more than ±1.65%.