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. 2000 Jul;130(6):1201–1210. doi: 10.1038/sj.bjp.0703413

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Copyright 2000, Nature Publishing Group

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Effects of drugs treatment on delayed alternation tasks in T-maze for each of the three delay intervals used. The range delays were: 2, 8 and 16 s. Results represent the number of correct and incorrect entries (means±s.e.mean; n=5) in the T-maze on 10 trials. Δ⁹-tetrahydrocannabinol showed a significant effect on delayed response performance (For correct entries: ANOVA main effect F_1.4=12.08, P<0.05; For incorrect entries: ANOVA main effect F_1.4=16.12, P<0.05). At each delay SR141716A and S(−)-sulpiride reversed the Δ⁹-tetrahydrocannabinol reduction of working memory, while (−)-quinpirole potentiated the inhibition of working memory induced by Δ⁹-tetrahydrocannabinol (all statistical comparisons revealed significant with P<0.001). s.e. were not more than ±1.56%.