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Competition binding profiles for AngII (a) and for the non-peptide antagonist L-159,809 (b) in cells transfected with the wild type (WT) and with the T88H mutant of the rat AT1 receptor. Data are expressed as percentages of the maximum specific binding of the radioligand 125I-L-735,286 (mean±s.e.mean, n=4–12).
