Figure 5.

The effect of some adjunctive drugs on the CAT gene transcription induced by corticosterone (1 μM, 2 h) in LMCAT cells. The drugs were used at the indicated concentrations for 5 days. Corticosterone (1 μM) was added 2 h before harvesting the cells for an assay of CAT enzyme activity (presented as fold induction in CAT activity). The data are presented as mean±s.e.mean, and the significance of differences between the means was evaluated by the Dunnett's test following a two-way analysis of variance (^*P<0.05; ^**P<0.001 vs respective control group).