Figure 3.

Effect of ruthenium red on relaxant responses to methanandamide (mAEA) and capsaicin in the rat isolated mesenteric arterial bed pre-constricted with methoxamine. (a) Concentration-response curves to mAEA under control conditions (n=4), and in the presence of ruthenium red at 0.1 μM (n=6) and 1 μM (n=4). (b) Dose-response curves to capsaicin under control conditions (n=6), and in the presence of ruthenium red at 0.1 μM (n=6) and 1 μM (o, n=4). Data are shown as means and bars indicate s.e.mean.