Figure 3.

The effect of 7 days paroxetine (3 mg kg⁻¹ day⁻¹, p.o., Veh/Par) or WAY100635 (1 mg kg⁻¹ day⁻¹, s.c., WAY/Veh) alone, or in combination (WAY/Par) compared to vehicle treated controls (Veh/Veh) on rat behaviour in the high-light social interaction test. (a) Neither paroxetine nor WAY100635 had an effect on interaction time when administered alone, but produced a significant elevation in interaction time compared to vehicle treated controls (Veh/Veh) when administered in combination (WAY/Par). (b) No effect on locomotor activity was seen in any treatment group relative to vehicle treated controls. Results are presented as mean±s.e.mean. ^**P<0.01 from vehicle-treated controls after two-way ANOVA. n=10–12 per group.