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Effect of PTX treatment (10 μg kg−1 3 days before the experiment) on SPPC-induced vasoconstriction in rat mesenteric microvessels in vitro. Data are mean±s.e.mean (n=16–17) and normalized as % of maximal noradrenaline values (≈20 mN). In microvessels of PTX-treated rats, the SPPC-induced vasoconstriction was significantly reduced compared to vehicle-treated animals (P<0.05, see results).
