Figure 2.

The effect of SB 203580 on BAL TNF-α levels in sensitized Brown Norway rats. SB 203580 (10-100 mg kg⁻¹) or vehicle (2 ml kg⁻¹) were administered orally 30 min prior to challenge and BAL TNF-α production was measured 1 h after aerosolized ovalbumin challenge. Group size was 12 with results expressed as mean±s.e.mean. †P<0.05 compared to unchallenged (unchall) group, pretreated with vehicle. ^*P<0.05 compared to challenged group, pretreated with vehicle.