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Concentration-response curves for NO-induced relaxation in U46619 pre-contracted tissue in the absence and presence of guanylyl cyclase inhibitors: 10 μM methylene blue and 10 μM ODQ. Effect of ODQ in the presence of 4-AP or 4-AP and TEA on NO-induced relaxation in U46619 pre-contracted HUA. Each point represents the arithmetic mean±s.e.mean of n=5–7 experimental determinations.
