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Effect of WIN 55212-2 on [3H]-ACh release from cortical synaptosomes evoked by (a) 1.3 mM calcium or (b) 11 mM potassium. Data are means (±s.e.mean) of eight determinations. ANOVA: 1.3 mM calcium, F(5,35)=3.7, P<0.01; 11 mM potassium, F(5,35)=2.4, P=0.057. *P<0.05, **P<0.01 versus control (Dunnett's test). Control values (fractional release): 1.3 mM calcium, 0.0184±0.0018; 11 mM potassium, 0.0303±0.0024.
