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. 2000 Oct;131(4):673–682. doi: 10.1038/sj.bjp.0703613

Figure 5.

Figure 5

Mean concentration-response curves to (a) spermine NONOate (n=4) and (b) FK409 (n=4) on rat main pulmonary arteries pre-contracted with phenylephrine (0.1 μM) in the absence of any inhibitor (control), in the presence of 10 μM ODQ alone and in the presence of 10 μM ODQ plus 1 mM ouabain. Relaxation responses are expressed as % reversal of the phenylephrine-induced contraction. Points are mean values with s.e.mean shown by vertical bars except when smaller than the size of the symbols. ***Concentration-response curve significantly different from the corresponding curve in the presence of ODQ alone (P<0.001; two-way ANOVA).