Figure 3.
Effect of co-treatment with quercetin (5–25 μM) (A), resveratrol (5–25 μM) (B) and (+)-catechin (1–10 μM) (C) on either 100 μM SNP-induced intracellular ROS in rat hippocampal cell cultures. Phenolic compounds were applied at the onset of SNP exposure. ROS were determined 20 h after by quantification of DCF fluorescence as described in Methods. Values represent mean±s.e.mean from 3–5 independent experiments. #P<0.05, ##P<0.01 compared to groups treated with vehicle, *P<0.05, **P<0.01 compared to groups treated SNP.