Figure 3.

Group data from experiments summarizing the effects of mibefradil (n=6) and nifedipine (n=5) on basal, minimum and steady-state diameter (A and B), and basal, maximum and steady-state Ca²⁺_i (C and D) responses occurring during a pressure step from 50 to 120 mmHg. See text for methods of determining maximum and steady-state values. Diameters are expressed as per cent of the basal diameter (50 mmHg) in the absence of Ca²⁺ channel antagonists. Changes in intracellular Ca²⁺ are presented as a percent of the pre-stimulation ratio value independent of the effect of the Ca²⁺ channel antagonists (C and D). Results are presented as mean±s.e.mean; ^*P<0.05 compared to corresponding value in the absence of antagonist; ΔP<0.05 compared to basal value at a given antagonist concentration.