Figure 5.

Comparison of the effects of mibefradil and nifedipine on arteriolar membrane potential (n=4 per group). At 10 mmHg vessels lack myogenic tone due to insufficient distending pressure while 70 mmHg approximates the in vivo pressure within the cremaster muscle 1A (Hill et al., 1992). Effects in the presence of mibefradil are shown on the left and in the presence of nifedipine in panels on the right. Results are presented as mean±s.e.mean; ^*P<0.05 compared to corresponding value in the absence of antagonist; ΔP<0.05 compared to value at 10 mmHg at a given antagonist concentration.