Figure 4.

Time-course of dissociation of specific [³H]-BWA868C binding to human platelet homogenates. (a) [³H]-BWA868C (5 nM) binding was conducted up to equilibrium and the dissociation was then initiated by the addition of 100 μM unlabelled PGD₂ and the residual specific binding monitored over time at room temperature. (b) shows the linear transformation of the data in (a). Plots shown are representative of ⩾ three experiments. Vertical lines show s.e.mean within the same experiment.