Blockade by the annexin 1 antisense oligodeoxynucleotide (ODN, 50 nM), but not by the scrambled or sense ODN sequences (50 nM), of the inhibitory effects of corticosterone (1 nM) on the release of ir-GH from freshly dispersed rat anterior pituitary cells induced in vitro by (a) growth hormone releasing hormone (GHRH, 10 nM), (b) forskolin (100 μM) and (c) 8-Br-cyclic AMP (1 μM). Each column represents the mean±s.e.mean (n=6); **P<0.01 vs corresponding secretagogue-free control; ††P<0.01 vs corresponding corticosterone-free control; NS=not significant; ANOVA+Duncan's multiple range test. Typical data from 3–4 replicate experiments.