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iNOS immunostaining in the paw of a rat at 35 days of collagen-induced arthritis (A). A marked increase in iNOS-like immunoreactivity is evident in the paws in arthritis. There was a marked reduction in the immunostaining in the paw of cloricromene-treated rats (B). Original magnification: ×125. Figure is representative of at least three experiments performed on different experimental days.
