Figure 3.

Cumulative concentration-relaxation curves to the PAR2-activating peptide, SLIGRL in the presence of either N^G-nitro-L-arginine (L-NOARG, 100 μM), oxyhaemoglobin (oxyHb, 20 μM) or indomethacin (3 μM) in rat isolated trachea (a), main bronchi (b) and intrapulmonary bronchi (c) contracted to ≈50% F_max with carbachol. Values are expressed as percentage (mean±s.e.mean) relaxations of the carbachol-induced contraction (n=6–12). ^*Denotes maximum values significantly different from controls (P<0.05).