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. 2000 Dec;131(8):1793–1799. doi: 10.1038/sj.bjp.0703754

Figure 1.

Figure 1

The concentration-dependent effect of eicosapentaenoic acid (EPA) in aortic rings (intact and de-endothelialized, E-) contracted with noradrenaline (NA, 1 μM) +indicates incubation (20 min) with indomethacin (INDO, 10 μM) or L-NAME (LN, 100 μM) in NA-contracted rings. The responses to EPA in Bay K 8644 (1 μM)- and potassium chloride-(KCl, 80 mM) contracted rings are also depicted as Bay K 8644-EPA and KCl-EPA, respectively. n=3–15 per group. *Indicates significance at P<0.05, **P⩽0.01, ****P⩽0.0001 as compared to EPA group.