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Time course for the decrease in mean arterial blood pressure and increase in heart rate in response to intra-arterial injection of (a) dKD (1 ;μmol kg−1) or (b) BK (1 ;μmol kg−1) in green monkeys. Heart rate before dKD or BK injection was 157±3 and 153±4 b.p.m., respectively. Animals were anaesthetized 4 h after intravenous injection of LPS (90 ;μg kg−1). * Significantly different (P<0.05) from pre-injection values (n=6 per group).
