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Low potency of organic nitrates in basilar versus coronary artery segments as indicated by the fold increase in the IC50-values. Given are the ratios of the halfmaximal effective concentration of the spontaneous NO-donor S-nitroso-N-acetyl-D,L-penicillamine (SNAP) and the organic nitrates glyceryl trinitrate (GTN) and isosorbide-5-nitrate (ISMN) in cardinal numbers (halfmaximal effective concentration, see Table 1).
