Figure 4.

Concentration-response curves to the NO donors SIN-1 (A, 0.03 – 3 μM), hydroxylamine (B, 0.01 – 1 μM), S-nitrosocysteine (C, 1 – 100 nM) and S-nitrosoglutathione (D, 1 – 1000 nM) in the mouse gastric fundus in control conditions and in the presence of 10 μM neocuproine. Results are expressed as percentage decrease of the prostaglandin F_2α-induced contraction and shown as mean±s.e.mean for n=4 – 6 experiments. ^*P<0.05 is considered as significantly different from control, Student's t-test for paired values.