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. 2001 Jan;132(1):252–258. doi: 10.1038/sj.bjp.0703782

Figure 2.

Figure 2

Effect of the left sciatic nerve denervation on the contralateral treatment with U-50,488H. Changes in HWLs to mechanical (A) and thermal (B) stimulation and volume (C) of the right hindpaw injected with carrageenan are shown. The left hindpaw was given either saline, or 0.3 or 2 mg of U-50,488H (U-50) or 1 mg of morphine. Data are presented as percentage (%) changes and expressed in mean±s.e.mean (vertical axis). Horizontal axis indicates hours (h) following injection. Significant differences are denoted as (*) morphine versus saline and (+) 2 mg of U-50,488H versus saline, 0.3 mg of U-50,488H and morphine. ANOVA and Student's t-test. n=8 – 10. * and+P<0.05; ++P<0.01; ***P<0.001.