Figure 1.

Effect of pregabalin in the rat elevated X-maze. Pregabalin (3.30 mg kg⁻²) or CDP (chlordiazepoxide, 3 mg kg⁻¹ s.c.) was administered s.c. 40 min before test. The time (a: TOA) and per cent time spent (b: % TOA) on open arms and time spent in the end half sections of the open arms (c: TEOA) together with total arm entries (d: TE) were measured. The duration of each test was 5 min. Results are shown as the mean (vertical bars represent ±s.e.mean) of 7 – 10 animals per group. ^**Significantly different from vehicle treated controls P<0.01 (ANOVA followed by Dunnett's t-test).