Figure 3.

The inhibition of MEK and Src. The effect of (A) the selective MEK1 inhibitor, PD 98059 (40 μM), and (B) the Src inhibitor, PP1 (200 nM), on the release of tritium from CHO h sst₂ cells stimulated by somatostatin (SRIF) and angiopeptin (AP; both 1 μM) in the presence and absence of pertussis toxin (100 ng ml⁻¹; 18 h). Results are expressed as a percentage of the somatostatin response in the absence of pertussis toxin. ^*Significantly different from somatostatin alone (P<0.05). Vertical lines represent the s.e.mean (n=5).