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. 2001 Feb;132(3):778–784. doi: 10.1038/sj.bjp.0703863

Figure 3.

Figure 3

Effect of glibenclamide, tolbutamide and probenecid on calcein accumulation in MRP1-overexpressing GLC4/Sb30 cells. Cells were incubated with 0.5 μM calcein AM in the absence or presence of 50 μM glibenclamide, 500 μM tolbutamide or 5 mM probenecid. Intracellular calcein accumulation was then determined by fluorimetry. The values are expressed as fluorescence arbitrary units (FAU) normalized to protein content and are the mean±s.d.mean of at least three independent experiments in triplicate. *P<0.05 when compared to control cells.