Figure 2.

Correlation between the functional affinities (pK_B values) of muscarinic antagonists at muscarinic receptor(s) in dog urinary bladder smooth muscle and binding affinities (pK_i) at human recombinant muscarinic receptors (m₁ – m₅; a – e respectively). The binding data were taken from Nilvebrant et al., 1996; Eglen et al., 1997; Hegde et al., 1997; Loury et al., 1999. The broken line is the line of identity (x=y) while the solid line is the correlation plot (the inserts give the correlation factors (r) and the sum of squares values (ssq)).