Figure 1.

Comparison of the effects of LPS and IFN-γ on arginase activity and nitrite accumulation of AMΦ. Cells were cultured for 20 h under control conditions or in the presence of 1 μg ml⁻¹ LPS or IFN-γ (100 or 500 u ml⁻¹). The cells were lysed and the arginase activity was determined (A). The culture medium was collected and analysed for nitrite accumulation (B). Results are expressed in absolute terms for nitrite accumulation or as per cent of the mean value of the controls of the respective cell preparation for arginase activity. Given are means+s.e.mean of 6 – 12 experiments. ^**P<0.01 when compared with the respective control value (Ctr.).