Effect of L-NOARG (100 μM), indomethacin (30 μM), L-NOARG+indomethacin, or CHAPS (4 mg ml−1 during 15 s) on the vasodilator responses to Tyr(Me)8BK (1 and 10 nM) and ACh (3 and 30 nM) in the isolated perfused rat kidney. Results are given as means±s.e.mean with the number of individual experiments in brackets. aP<0.05, bP<0.01, cP<0.001 vs control; *P<0.05, ***P<0.001 for other comparisons as indicated.