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Dose dependency and kinetics of neutrophil accumulation in the pleural cavity in response to KC or MIP-2. (a) increasing doses of KC or MIP-2 (0.01–0.1 μg) induced a significant neutrophil accumulation at 2 h when compared with PBS-treated controls. (b) Time course of neutrophil accumulation. Values represent the mean±s.e.mean of six mice. *P<.05 and **P<0.01 compared with PBS, and #P<0.05 compared to KC 0.01 μg by one-way ANOVA followed by Student-Newmann-Keuls post-test.
