Figure 4.
Consumption of the contact system components in rabbit plasma by in vivo treatments as assessed by in vitro formation of immunoreactive BK and des-Arg9-BK. Blood has been sampled in anaesthetized animals before and 90 min after injection of either LPS or dextran sulphate at the indicated doses. Then, the contact system was maximally activated using glass beads, and the plasma was periodically sampled for the measurement of immunoreactive kinins (see text). Values are the means±s.e.mean of three determinations in each group.