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. 2001 Aug;133(7):1163–1171. doi: 10.1038/sj.bjp.0704163

Figure 1.

Figure 1

Dose and time-dependent expression of COX-2 by SIN-1. HUVEC were incubated for 6 h with different concentrations of SIN-1 or Molsidomine, the inactive precursor of SIN-1. COX-2 and COX-1 expression was evaluated by Western blot analysis using specific antibody for each isoform. (a) Effect of increasing concentrations of SIN-1 on COX-2 and COX-1 protein. Molsidomine, the inactive precursor of SIN-1, was tested on COX-2 expression. (b) Time-course of COX-2 induction by SIN-1. Results are representative of three different experiments.