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Effect of balloon distension (0.5 and 1 ml) or intraluminal acetic acid (0.5 ml of 7.5% v v−1 in saline) application on colonic motility: (a) AUC, area under the curve; (b) MAC, maximal amplitude of contractions; (c) minimal pressure. Results are expressed as difference (Δ) in respect to baseline values. Fisher LSD test: *P<0.05 and **P<0.01 vs time-matched Vehicle-0.5 ml. Each point and bar represents the mean±s.e.mean of 12 experiments.
