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The effect of [βAla8]NKA(4-10) (10 nmol kg−1, i.v.) on colonic motility. A representative tracing (32 experiments) of the effect of [βAla8]NKA(4-10) (vertical line) in control preparations (balloon filled with 0.5 ml) (a). [βAla8]NKA(4-10) increases the amplitude of contractions (MAC) and minimal pressure. The effect of atropine (n=16) or hexamethonium (n=16) on MAC (b). The effect of atropine or hexamethonium on minimal pressure (c). Fisher LSD test: *P<0.05 and **P<0.01 vs CTR.
