Figure 2.

AChE enhances [³H]-FW but not [³H]-kainate binding to rat brain sections. Autoradiographs show [³H]-kainate (A,B,D,E) and [³H]-FW (C,F) binding to brain sections from adult rats 1 u ml⁻¹ AChE evoked increased [³H]-FW binding but did not significantly affect [³H]-kainate binding. Note that whereas [³H]-FW non-specific binding was negligible (less than 3% of total, autoradiographs not shown), [³H]-kainate non-specific binding (A,D) represented ∼50% of total binding. Independently from the agonist used, AChE alone (D) did not affect non-specific binding. Abbreviations, as in Figure 1; py(CA3), pyramidal cell layer of hippocampus (CA3 field); vlTh, ventrolateral thalamus; vmH, ventromedial hypothalamus; vmTh, ventromedial thalamus.