Figure 5.

Vasoconstrictor responses (expressed as per cent reduction of vascular conductance compared to basal) evoked in (a) spleen and (b) kidney by the NPY Y₁ receptor agonist [Leu³¹Pro³⁴]NPY (23–230 pmol kg⁻¹, i.v.), in the anaesthetized pig. The vascular responses are shown before (control) and after treatment with the NPY Y₂ receptor antagonist BIIE0246 (100 nmol kg⁻¹, i.v.). Data are given as means±s.e.mean, n=7. There were no significant differences compared to control.