(A) Comparison of the contractile effects of H2O2 (5×10−4 M) on the mesenteric artery (MA) and the aorta, with (E+) or without (E−) endothelium, from SHR and WKY. *P<0.05, **P<0.01 compared with aorta; (B) Contraction to H2O2 (5×10−4 M) in E+ and E− aorta from SHR and WKY. **P<0.01, compared with WKY aorta, #P<0.05 compared with E+ rings. Results (mean±s.e.mean) were from 6 – 11 rats and expressed as the percentage of the contraction elicited by 80 mM KCl.