Figure 2.
Effects of treatment with mexiletine or crobenetine on stance of the rats injected in the ankle joint with CFA (n=6 per group). Rats injected with mineral oil and those treated with 4 mg kg day−1 meloxicam are also shown for comparison, n=12 for each group. (A) The responses obtained 24 h after induction of arthritis. (B) The responses obtained 48 h after induction of arthritis. (C) The responses obtained 96 h after induction of arthritis. Results are expressed as mean±s.e.mean. *Denote those groups in which the response was significantly different from the vehicle-treated CFA group (P<0.05).