Figure 1.

Effects of [Gly¹⁴]-humanin on scopolamine-induced impairment of spontaneous alternation behaviour in the Y-maze test. Mice were treated with scopolamine HBr (1 mg kg⁻¹ s.c.) and [Gly¹⁴]-humanin (pmol 5 μl⁻¹ i.c.v.) 30 and 15 min before the Y-maze test, respectively. The results are expressed as the mean±s.e.mean. The number of mice used is indicated in each column. **P<0.01 vs saline+([Gly¹⁴]-humanin 0 pmol), #P<0.05 vs saline +([Gly¹⁴]-humanin 0 pmol) by Dunnett multiple comparisons test.