Figure 2.

Serum thiobarbituric acid reactive substances and sciatic nerve conjugated diene level. Serum samples were collected and used to determine thiobarbituric acid reactive substances level (left side of figure). The sciatic nerve was also collected and a portion used to determine the conjugated diene level (right side of figure). Data are presented as the mean±s.e.mean for 17 control rats, 14 untreated diabetic rats and 11 diabetic rats treated with M40403. The * denotes a significant difference compared to control, P<0.05. The+denotes a significant difference compared to untreated diabetic rats, P<0.05.