Figure 1.

Pretreatment with either apstatin, an inhibitor of aminopeptidase P, ramiprilat, an inhibitor of angiotensin converting enzyme, or their combination was followed by 30 min of coronary artery occlusion and 3 h of reperfusion. HOE140, an antagonist of B₂-receptors, was used to investigate the influence of kinins. The ratio between area at risk (AAR) and left ventricle (LV) was used as an indicator for a constant placement of the coronary ligature. There were no significant differences between the groups. Data are given as means±s.e.mean (n=5).