Figure 2.

Concentration-response curves for relaxations of the mouse anococcygeus muscle in response to TRIM when tone is raised by either 100 nM thapsigargin (Tg; in the presence of 10 μM verapamil) or high K (60 mM). Measurements were taken 4 min after addition of TRIM to the bath. Each point is the mean±s.e.mean from a minimum of five individual muscle preparations. ^*P<0.05, significant relaxation.