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Effect of increasing vascular tone with neuropeptide Y (NPY, n=6), 4-amidopyridine (4-AP, n=6), the calcium ionophore A23187 (n=6) and the nitric oxide synthase inhibitor Nω-nitro-L-arginine methyl ester (L-NAME, 100 μM, n=7) on contractile responses to 5-carboxamidotryptamine (5-CT, control: n=12) in control rat isolated small muscular pulmonary arteries. Responses are shown as the percentage response to a contraction to 50 mM KCl. Data is shown as means±s.e.mean. n=number of rats.
