Comparison of the effects of treatment with corticosterone (Cort, 500 μg kg−1, i.p.) and annexin 1Ac2 – 26 (0.1 – 10 ng rat−1, i.c.v.) on the resting plasma ACTH (a), serum GH (b) and serum LH (c) concentrations in rats and on the responses to IL-1β (10 ng rat−1, i.c.v.). Values represent the mean±s.e.mean (n=6). *P<0.05, **P<0.01 vs annexin 1 vehicle alone (Veh, 3 μl rat−1). ††P<0.01 vs IL-1β alone (ANOVA plus Duncan's test).