Figure 5.

Effect of intrathecal injections of a PKC inhibitor, chelerythrine chloride (1, 10.4, 104.2 nmol rat⁻¹, n=8/dose) or vehicle (10 μl rat⁻¹, n=8) on the time-course of the vocalization threshold of Mg-deficient and control rats submitted to the paw pressure test (A). AUC was calculated throughout the period of 120 min for each dose in Mg-deficient rats (B). Results are expressed as means±s.e.mean. ^*P<0.05, ^**P<0.01 and ^***P<0.001; compared to the vehicle-treated groups of Mg-deficient rats.