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Effects of Bunodosoma granulifera toxins on the resting and action potential characteristics of rat ventricular strips. Both BgII (A) and BgIII (B) were applied at a concentration of 10 μM. Within 1 min, both toxins markedly increased the action potential duration. After a longer time (5 min) the resting potential was decreased. Note that the increase in action potential duration and the decrease in resting potential were more marked with BgII.
