Figure 8.

Effect of Wortmannin and LY294002 on VEGF-induced activation of the p42/44 and p38 MAPK. (A) Confluent BAEC were pretreated with or without Wortmannin (Wort; 100 nM) or LY294002 (LY; 10 μM), and were stimulated and processed as described in Figure 3A. Western blot analysis was performed with an anti-phospho-p42/44 MAPK antibody. (B) Confluent BAEC were pretreated with or without Wortmannin (Wort; 100 nM) or LY294002 (LY; 10 μM), and were stimulated and processed as described in Figure 3B. Western blot analysis was performed with an anti-phospho-p38 MAPK antibody.