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Effect of endothelin-1 (ET-1; 1 nM) on EFS standard induced contraction (a stimulus frequency that induced a 30% of contraction induced by an EFS of 30 Hz) prior to and 30 min after pretreatment with tachykinin NK2 receptor antagonist (SR 48968: 0.01 – 1 μM). Values are per cent of contraction induced by an EFS of 30 Hz. *P<0.05, **P<0.01. Data are expressed as the means±s.e.mean from eight preparations.
