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Effect of SR 48968 (0.1 μM) pre-treatment on acetylcholine (ACh; A), endothelin-1 (ET-1; B), and EFS (C) induced bronchial smooth muscle contraction. Data are expressed as per cent of the response to a maximally effective concentration of carbachol (10 μM; 100% Cmax). Values are the means±s.e.mean from eight preparations.
